Met and the microenvironment
نویسندگان
چکیده
منابع مشابه
HGF/c-MET Axis in Tumor Microenvironment and Metastasis Formation
Tumor metastases are responsible for approximately 90% of all cancer-related deaths. Metastasis formation is a multistep process that requires acquisition by tumor cells of a malignant phenotype that allows them to escape from the primary tumor site and invade other organs. Each step of this mechanism involves a deep crosstalk between tumor cells and their microenvironment where the host cells ...
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The metastatic spread of tumor epithelial cells accounts for over 90% of cancer-specific mortality; however, the molecular mechanisms that govern tumor spread and distant recolonization remain unclear. In this issue of JCI, Rokavec and colleagues shine light on this murky aspect of tumor biology by focusing through the lens of microenvironmental contributions, namely inflammation, as driving si...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2011
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.5.3.15258